Tokyo stocks opened lower on Wednesday, with investors vigilant against short-term overheating and searching for clues after a US market holiday.The benchmark Nikkei 225 index was down 0.69 percent, or 229.99 points, at 33,192.53 in early trade, while the broader Topix index lost 0.44 percent, or 10.12 points, to 2,296.25.
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